Abstract
A mass spectrometric investigation on the anti-inflammatory drug o-(2,6-dichlorophenyl)aminophenylacetic acid (Diclofenac) and its hydroxylated metabolites is performed by means of electron impact, chemical ionization and fast atom bombardment. Tandem mass spectrometry of isomeric monohydroxylated compounds allows assessment of the substitution pattern on the two aryl rings.
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