MOLECULAR CHAPERONES AND CELL SIGNALLING

Abstract

Preface Part I. Molecular Chaperones and the Cell Stress Response: 1. Chaperone function: the orthodox view R. J. Ellis 2. Intracellular disposition of mitochondrial molecular chaperones: Hsp60, mHsp70, Cpn10 and TRAP-1 R. S. Gupta, T. Bowes, S. Sadacharan and B. Singh Part II. Changing Paradigms of Protein Trafficking and Protein Function: 3. Novel pathways of protein secretion G. Chimini and A. Rubartelli 4. Moonlighting proteins: proteins with more than one function C. J. Jeffery 5. Molecular chaperones: the unorthodox view B. Henderson and A. Shamaei-Tousi Part III. Molecular Chaperones as Cell Regulators: 6. Cell-cell signalling properties of chaperonins A. R. M. Coates 7. Toll-like receptor-dependent activation of antigen presenting cells by Hsp60, Hsp70 and Gp96 R. M. Vabulas and H. Wagner 8. Regulation of signal transduction by intracellular and extracellular Hsp70 A. Asea and S. Calderwood 9. Hsp72 and cell signalling M. Y. Sherman 10. Heat shock proteins, their cell surface receptors and effect on the immune system T. Lehner, Y. Wang, T. Whittall and L. A. Bergmei 11. Molecular chaperone-Cytokine interactions at the transcriptional level A. Stephanou and D. S. Latchman Part IV. Physiological and Pathophysiological Signals: 12. Heat shock protein release and naturally-occurring exogenous heat shock proteins J. Frostegard and A. G. Pockley 13. Hsp27 as an anti-inflammatory Protein K. Laudanski, A. De and C. Miller-Graziano 14. Bip, a negative immune regulator involved in rheumatoid arthritis V. M. Corrigal and G. S. Panayi Part V. Molecular Chaperones as Therapeutics: 15. Neuroendocrine aspects of the molecular chaperones ADNF and ADNP I. Gozes, I. Vulih, I. Spivak-Pohis and S. Furman 16. Heat shock proteins regulate by both molecular and network cross-reactivity F. J. Quintana and I. R. Cohen 17. Heat shock protein fusions: a platform for the induction of antigen-specific immunity L. Mizzen and J. Neefe 18. Molecular chaperones as inducers of tumour immunity P. P. Bannerjee and Z. Li Part VI. What Does the Future Hold?: 19. Gazing into the crystal ball: the unfolding future of molecular chaperones L. Hightower.