Abstract

Section I: Principles of Molecular Cardiology. General Principles of Molecular Biology. Genetic Approaches to Cardiovascular Disease. Genetically Modified Animal Models in Cardiovascular Research. Gene Transfer Approaches for Cardiovascular Disease. Section II: Morphogenesis and Cardiovascular Diseases. Molecular Advances in Cardiovascular Development. Molecular Genetics of Congenital Heart Disease. Inherited Vascular Disease. Section III: Cardiac Muscle and Myopathies. Structure and Function Relationships in Contractile Proteins. Molecular and Cellular Biology of Cardiac Hypertrophy and Failure. Gene Defects of Inherited Cardiomyopathies. Mitochondrial Genes in Myopathy, Cardiomyopathy and Stroke. Section IV: Cardiac Conduction and Arrhythmias. Normal Cardiac Electrophysiology. Molecular Basis of Inherited Cardiac Arrhythmias. Molecular Approaches to Arrhythmogenesis. Section V: Vascular Biology and Atherogenesis. Biology of the Vessel Wall: Endothelium. Atherogenesis and Inflammation. The Molecular and Cellular Biology of Coronary Restenosis. Angiogenesis in Cardiovascular Disease. Section VI: Risk Factors for Coronary Artery Disease. Disorders of Lipoprotein Metabolism. Lipoprotein Receptors and Cellular Cholesterol Metabolism in Health and Disease. Lipoproteins, Lipoprotein Oxidation, And Atherogenesis. Molecular Basis of Non-Insulin-Dependent Diabetes Mellitus. Section VII: Molecular Basis of Hemostasis Disorders. Blood Coagulation in Cardiovascular Disease. The Fibrinolytic System and Thrombolytic Therapy. Platelet Thrombus Formation and Anti-Platelet Therapy. Glossary of Molecular Genetics.

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