Abstract
The neural cell adhesion molecule L1 can be induced by antibodies in indirect immunofluorescence procedures to co-redistribute on the surface membrane of cultured mouse neuroblastoma cells with the 180 kDa component of N-CAM, but not with the 140 kDa component of N-CAM, the H-2 histocompatibility antigen or antigens recognized by polyspecific antibodies to mouse liver membranes. These observations indicate a differential and close molecular association between L1 and the N-CAM component with the larger intracellular domain.
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