Abstract
DURING the early cleavage stages of sea urchin embryos, the number of nuclei doubles in 2 h or less and the DNA doubles in about 10–12 min at 16° C1. A special relationship between nuclear DNA and DNA polymerase is suggested by the constant ratio of polymerase activity to DNA2,3. Evidence suggests that this proportionality is maintained by the translocation of the stored polymerase from the cytoplasm to the nucleus4.
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