Abstract
SummaryInspired by wireless communication systems, we propose a feasible downlink/uplink biocyber interface for the expected targeted drug delivery system based on Internet of Biological NanoThing (IoBNT) paradigm. The downlink/uplink biocyber interface of IoBNT comprises Fluorescence Resonance Energy Transfer (FRET) and Molecular Communication (MolCom) technology. On the downlink (from Internet to targeted nanonetwork), the biocyber interface transduces electromagnetic (EM) signal to biochemical signals, and thus with the help of mobile MolCom system based on FRET nanocommunication, the drug information delivers to the diseased cell within the targeted intrabody nanonetwork. On the uplink, the MolCom system consists of embedded sensor/actuator nanonetwork to detect the biochemical changes in the targeted cell, and hence biocyber interface transduces the biochemical signal to EM signal. As a result, the paradigm of IoBNT responses by proper functions to these changes according to the decision of medical health care. The performance analysis of the proposed IoBNT system is numerically investigated through MolCom system‐based FRET, while the performance evaluation is evaluated by employing spreading epidemic scheme in terms of successful probability of drug delivery, channel capacity, average drug‐delivery time, and throughput. The simulation results show that the proposed IoBNT is a promising paradigm for smart drug delivery system, and its performance is mainly based on the nanostructure and the characteristic of molecular nanomachines in the targeted nanonetwork.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
