Mola hidatiforme parcial: a propósito de un caso

Abstract

Gestational trophoblastic disease (GTD) is made up of a set of uncommon pathologies associated with pregnancy, ranging from benign to malignant; It has been described as several unusual benign and malignant processes, derived from an abnormal proliferation of the trophoblast of the human placenta, this groups a set of benign lesions such as hydatidiform mole and gestational trophoblastic neoplasia. Hydatidiform mole is a rare obstetric pathology, consisting of an abnormal pregnancy characterized by hydropic degeneration of the chorionic villi and trophoblastic hyperplasia, with a clinical presentation that warrants proper use of available diagnostic tests, especially ultrasound and Doppler , early in pregnancy, to establish its timely diagnosis, which will favorably improve the prognosis; In addition to performing histology, molecular genetic studies would be key to help in the diagnostic pathway. Its treatment of choice is uterine evacuation and strict monitoring with human chorionic gonadotropin (hCG), specifically of β-hCG levels, essential for early diagnosis of gestational trophoblastic neoplasia. High-risk trophoblastic disease (TGD) is treated with multidrug chemotherapy, with or without adjuvant surgery to remove resistant foci of disease, or radiation therapy for brain metastases.