MOEMS-Assisted Radial Pulse Measurement System Development

Abstract

Blood pressure is the first assessment of blood flow and still is the easiest parameter to measure. Examination of wrist radial pulse is non-invasive diagnostic method, which takes a very important place in traditional Chinese medicine. Hence, it lacks the consistency and reliability, which limits practical application in clinical medicine. Thus, the quantitative characteristics of the method of the wrist pulse diagnosis is a prerequisite for its further development and wide use. Noninvasive CCD sensor based on a hybrid measurement systems for the analysis of the radial pulse signals is developed. Various input pressure and fluids of different viscosity are used in the assembled artificial circulation system to test the effectiveness of laser triangulation technology to improve the detection sensitivity by a microfabricated MOEMS placed on a synthetic vascular graft and on the human wrist. MOEMS design methodology is presented. The simulation results provide the right to choose the form of the membrane. Technological process of formation of MOEMS is performed using advanced microfabrication technology. In “in vitro” and “in vivo” measurement results are adequate and suggest practical relevance of the proposed methodology.