Modulation of sensorimotor oscillation by sensory gating in the frontal cortex.

Abstract

To reveal that nonprimary motor-related areas located in the upper stream of the sensorimotor area are associated with self-regulated local electroencephalogram changes in the sensorimotor area during motor tasks. Among healthy participants, we measured the gating of somatosensory-evoked potentials (SEPs) in nonprimary motor-related areas and the sensorimotor area, and event-related desynchronisation, which reflects the excitability changes of the neurons localised in the sensorimotor area during motor execution and imagery. We confirmed significant correlations between beta-band event-related desynchronisation and the somatosensory-evoked potential gating of frontal N30 during motor imagery and execution (motor imagery: r = 0.723; P < 0.05; motor execution: r = 0.873; P < 0.05), and nonsignificant correlations between beta-band event-related desynchronisation and the somatosensory-evoked potential gating of N20 (motor imagery: r = 0.079; P > 0.05; motor execution: r = 0.449; P > 0.05). The N30 gating of SEPs, with which the beta-band event-related desynchronisation was associated, implies that they modulate sensory input to the supplementary motor area/premotor cortex during motor tasks, the beta-band self-regulated local electroencephalogram changes in the sensorimotor area related sensory input to the supplementary motor area/premotor cortex, and not to primary sensory area derived from N20 gating. This study suggests that some motor commands are derived from sensory gating in the supplementary motor area/premotor cortex.