Abstract
The effects of pertussis and cholera toxins on interleukin-1 (IL-1) stimulated collagenase production from rabbit articular chondrocytes were investigated. Cholera toxin (50-1000 ng/ml) had no significant effect on IL-1-stimulated collagenase production. Pertussis toxin gave a 50-100% inhibition of collagenase activity induced by submaximal IL-1 concentrations. However, pertussis toxin had little effect on collagenase activity induced by maximal concentrations of IL-1. Optimal inhibitory effects were observed with 5-10 ng/ml of toxin.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Paper version not known
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Paper Title
Journal
Date
