Abstract

VARIOUS hormones and drugs induce long-lasting alterations of electrical activity in certain neurones from the marine snail Aplysia californica1–5. Drugs and hormones were found to affect the lipid microviscosity of biological membranes6,7, so it is plausible that their effect on electrical activity is mediated by changes in membrane fluidity. We report here that by changing the cholesterol content of Aplysia neurones, which presumably increases its membrane microviscosity8, long term, though reversible, alterations in electrical activity are induced.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.