Abstract
Meeting abstracts The present study was planned to investigate the chemopreventive efficacy of Chrysin (CH) against renal carcinogenesis in Wistar rats. Ferric nitrilotriacetate (Fe-NTA) is a potent nephrotoxicant and known renal carcinogen. CH is a natural flavonoid found in honey, propolis, blue
Highlights
The present study was planned to investigate the chemopreventive efficacy of Chrysin (CH) against renal carcinogenesis in Wistar rats
Renal carcinogenesis is a multistep process and it originates from a series of molecular and histopathological alterations
Renal cancer was initiated by single intraperitoneal injection of N-nitrosodiethylamine and promoted chronically by twice weekly administration of Ferric nitrilotriacetate (Fe-NTA) for 16 weeks and rats were sacrificed after 24 weeks
Summary
The present study was planned to investigate the chemopreventive efficacy of Chrysin (CH) against renal carcinogenesis in Wistar rats. Modulation of chemically induced renal carcinogenesis by Chrysin via inhibition of oxidative stress, hyper-proliferation and inflammation at preclinical stage From 30th Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2015) National Harbor, MD, USA.
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