Abstract
ObjectiveTo evaluate the effects of ethyl acetate extract of Curcuma longa against modulation of glucose uptake and adipogenesis in cell line models. MethodsWe used 3T3L1 and L6 cells to investigate cytotoxicity, glucose uptake with 2-NBDG as probe and adipogenesis. All the analysis was done with flowcytometry. ResultsThe results showed that the extract did not possess any significant glucose uptake activity but it exhibited significant adipocyte differentiation potential. ConclusionsEthyl acetate extract of Curcuma longa exhibits significant antiadipogenesis and can be used as an effective drug for the treatment of obesity and other associated complications.
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