Abstract
Aim:In the present study, the immunomodulatory effects of roots of Gmelina arborea Linn. were investigatedMaterials and Methods:Methanolic extract of G. arborea Linn. (MEGA) and its ethyl acetate fraction (EAFME) were used for evaluating the pharmacological activity. The modulating effect was evaluated on humoral and cell-mediated immune response using animal models like cyclophosphamide-induced myelosuppression, delayed-type hypersensitivity (DTH) response, and humoral antibody (HA) titreResults:Both test extracts produced significant increase in HA titre, DTH response, and levels of total white blood cell countConclusion:This drug is found to be a potential immunostimulant
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