Abstract

Rational prescribing tools can be used by individual prescribers, organisations, and researchers to evaluate the quality of prescribing for research and quality improvement purposes. A literature search showed that there is only one tool for evaluating rational prescribing for paediatric patients in hospital and outpatient settings. The Pediatrics: Omission of Prescriptions and Inappropriate Prescriptions (POPI) tool was developed in France and comprises 105 criteria. The aim of this study was to modify this tool to facilitate its use in paediatric practice in the United Kingdom (UK). POPI criteria were compared to relevant UK clinical guidelines from the National Institute for Health and Care Excellence, the Scottish Intercollegiate Guideline Network and the British National Formulary for Children. Where guidelines differed, criteria were modified to reflect UK guidance. If there were no relevant guidelines or directly contradictory guidelines, criteria were removed. Overall, no change was made to 49 criteria. There were 29 modified to concord with UK guidelines. Four criteria were reduced to two criteria due to being linked in single guidelines. Twenty-three criteria were omitted, due to the absence of relevant UK guidance or directly conflicting UK practice, including one entire clinical category (mosquitos). One category title was amended to parallel UK terminology. The modified POPI (UK) tool comprises of eighty criteria and is the first rational prescribing tool for the evaluation of prescribing for children in hospital and outpatient settings in the UK.

Highlights

  • Rational prescribing describes practices aimed to optimise the use of medicines, encompassing safety, clinical effectiveness, access, and financial considerations

  • There are currently no areas in the United Kingdom (UK) where insect-borne diseases are endemic. This was not considered applicable to UK practice and the category comprising of seven propositions, was removed

  • Erythromycin is recommended for people who are allergic to penicillin, at a dose of: 125 mg twice a day for infants and children up to two years of age. 250 mg twice a day for adults and children older than two years of age.)

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Summary

Introduction

Rational prescribing describes practices aimed to optimise the use of medicines, encompassing safety, clinical effectiveness, access, and financial considerations. Rational prescribing tools have been used, in older adult medicine, as both research and quality improvement tools to investigate and improve rational prescribing [4]. These tools provide their users, whether individual prescribers, organizations, or research groups, with an objective measurement tool for the quality of prescribing according to rational prescribing principles. This facilitates research into factors involved in irrational prescribing, comparison across time or between

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