Abstract
Objectives Bioglass composites and polymers are materials of great interest for the medical and dental areas due to their properties, combining the bioactivity of ceramic materials and the mechanical properties of polymers. The purpose of the present study was to develop and to characterize the physicochemical and morphological properties an experimental bioglass-based ternary composite composed associated with sodium carboxymethylcellulose (Na-CMC) and polyvinyl alcohol (PVA). The compatibility of functional groups with bioglass was previously evaluated. The composite was then synthesized and evaluated in terms of morphology, elemental composition, compressive strength, porosity, and bioactivity. Materials and Methods The bioglass was previously synthesized using a sol-gel route and characterized using FTIR analysis to identify the functional groups. The bone graft composite was then synthesized associating the bioglass with PVA, surfactant Triton X, and Na-CMC. The composite was then morphologically characterized using SEM/EDS. The porosity of the composite was analyzed using µCT, which also provided the composite compression strength. The composite was then evaluated in terms of its bioactivity using SEM/EDS analyses after immersion in SBF for 12, 24, 48, and 72 h. Results FTIR analysis confirmed, among other components, the presence of Si–O–Ca and Si–O–Si bonds, compatible with bioglass. SEM analysis exhibited a composite with a porous structure without spikes. The elemental mapping confirmed the presence of Si, Ca, and P in the composite. µCT analysis demonstrated a porous structure with 42.67% of open pores and an average compression strength of 124.7 MPa. It has also demonstrated ionic changes in the composite surface after immersion in SBF, with increasing detection of Ca and P as a function of time, highlighting its chemical bioactivity. Conclusions It can be concluded that the proposed bioglass-based composite presents a three-dimensional, well-structured, chemically bioactive porous structure, mechanically resistant for being reinforced with polymeric phases, with promising results as a synthetic bone graft, which makes it suitable for guided bone regeneration.
Highlights
ObjectivesBioglass composites and polymers are materials of great interest for the medical and dental areas due to their properties, combining the bioactivity of ceramic materials and the mechanical properties of polymers. e purpose of the present study was to develop and to characterize the physicochemical and morphological properties an experimental bioglass-based ternary composite composed associated with sodium carboxymethylcellulose (Na-CMC) and polyvinyl alcohol (PVA). e compatibility of functional groups with bioglass was previously evaluated. e composite was synthesized and evaluated in terms of morphology, elemental composition, compressive strength, porosity, and bioactivity
The present study proposed the development of this experimental bioglassbased composite for guided bone regeneration. e present study aimed to develop and characterize an experimental bone graft based on a ternary composite composed of bioglass, sodium carboxymethylcellulose (Na-CMC), and polyvinyl alcohol (PVA)
Bands referring to carbonates are present at 1395 and 1647 cm−1 and bands referring to hydroxyls at 3410 cm−1 [17, 18]. e peaks shown are compatible with the composition of a bioglass with a mass of 58% Si presented in the literature [14]
Summary
Bioglass composites and polymers are materials of great interest for the medical and dental areas due to their properties, combining the bioactivity of ceramic materials and the mechanical properties of polymers. e purpose of the present study was to develop and to characterize the physicochemical and morphological properties an experimental bioglass-based ternary composite composed associated with sodium carboxymethylcellulose (Na-CMC) and polyvinyl alcohol (PVA). e compatibility of functional groups with bioglass was previously evaluated. e composite was synthesized and evaluated in terms of morphology, elemental composition, compressive strength, porosity, and bioactivity. E composite was synthesized and evaluated in terms of morphology, elemental composition, compressive strength, porosity, and bioactivity. ΜCT analysis demonstrated a porous structure with 42.67% of open pores and an average compression strength of 124.7 MPa. SEM analysis exhibited a composite with a porous structure without spikes. ΜCT analysis demonstrated a porous structure with 42.67% of open pores and an average compression strength of 124.7 MPa It has demonstrated ionic changes in the composite surface after immersion in SBF, with increasing detection of Ca and P as a function of time, highlighting its chemical bioactivity. It can be concluded that the proposed bioglass-based composite presents a three-dimensional, well-structured, chemically bioactive porous structure, mechanically resistant for being reinforced with polymeric phases, with promising results as a synthetic bone graft, which makes it suitable for guided bone regeneration
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