Abstract

Fast neutron radiotherapy (FNT) has emerged as a favored modality for treatment of certain cancers, and FNT-enhanced neutron capture therapy (NCT) is a subject of increasing research interest. Unlike the current situation with clinical applications of epithermal neutron NCT, which rely primarily on nuclear reactors for the neutron source, FNT neutron sources are generated using particle accelerators. This yields a neutron source spectrum with a peak energy very near the particle beam energy, which is several orders of magnitude higher energy than used for epithermal NCT As with all medical applications of radiation, it is important that the dosimetric parameters of such neutron sources be well characterized, and that patient-specific treatment planning computations be performed for each clinical application.

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