Modifications of Serum Iron, Copper Concentration (SI, Cu), Total and Latent Iron-Binding Capacity (TIBC, LIBC), and Transferrin Saturation (TS) in Natural Babesia ovis Infection of Sheep

Abstract

The aim of this research is to find out the relationship between body temperature and serum iron parameters (SI, TIBC, LIBC and TS), copper as well as progression of a true iron deficiency in naturally Babesia ovis infected sheep. No etiologic or symtomatic therapy applied 15 Akkaraman sheep with rectal temperature above 40¼C had been used for this study. Acaprin, a babesiacidal drug, had been used for treatment of the disease. Hematological and biochemical parameters were determined in blood samples collected prior and after treatment (day 1 and 7). Hematocrit (Htc) value and hemoglobin concentration (Hb) have been considered for presence and degree of anemia. Serum total, direct and indirect bilirubin (TB, DB and IB), lactate dehyldrogenase (LDH) and total protein (TP) values have been considered for the determination of anemia type. A significant negative correlation between body temperature and SI, TIBC and TS (p