Abstract

Abstract The effect of three alcohols as representative of ointment and cream components on the radiation sensitivity of anoxic Bacillus pumilus spores was determined in order to understand the radiation-induced inactivation of spores when suspended in non-aqueous milieux. Bacillus pumilus spores mounted on aluminium silicate powder were suspended in the appropriate alcohol, deoxygenated and 60Co gamma-irradiated. Responses ranged between that for buffered suspensions alone to approximately twice that value. Concentrations of the alcohols in buffer, below their solubility limits, did not produce responses significantly different from that characteristic of anoxic buffer alone.

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