Abstract
Seven moderately hydrated male subjects experienced 1 hr. of exposure to 6 conditions of chair rest, immersion, and hypnosis on separate days. Head-out, neutral-temperature immersion produced significant diuresis characterized by increases in free-water clearance, osmolar clearance, and sodium excretion. Tubular reabsorption of sodium was not altered by immersion or hypnosis. Hypnotic suggestion of thirst significantly inhibited the diuretic response to immersion, principally by increased antidiuretic hormone activity. The estimated glomerular filtration rate was increased during immersion and reduced by the hypnotic suggestion of thirst. These data support the suggestion that appropriate hypnotic suggestion can significantly modify environmentally induced alterations in physiological performance.
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