Abstract
Anti-Rh (D) antibody has been demonstrated to be nonhemolytic to Rh-positive red blood cells. However, fetal macrophages in vitro have been shown to bind Rh-positive red blood cells which are coated with this antibody. Promethazine hydrochloride inhibits the ability of fetal macrophages to bind Rh-positive red blood cells in vitro. These data suggest macrophage-mediated red blood cell destruction in erythroblastosis fetalis and offer one explanation for the success of promethazine hydrochloride in ameliorating the effects of this disease.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Paper version not known
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
