Abstract
The effects of serotonin and caerulein on the electrical activity of the human small intestine has been investigated. In a dose of 2.5 mg intravenuously, serotonin induces a strong motor response, with an increase in slow-wave amplitude (P<0.01) and a decrease in frequency (P<0.001). The percentage of bursts of spike, their duration and amplitude increased significantly (P<0.01 andP<0.05). The administration of caerulein (2 ng/kg/minute intravenously) inhibited spike percentage duration in the first and second portion of the duodenum, and a significant increase in the third and upper small intestine. Caerulein caused a significant decrease in slow-wave frquency (P<0.01) at every level. The possibility that the above substances have a direct effect on pace-setter potential is discussed. The purpose of the present investigation is to study the effect of serotonin* and caerulein* on the electrical activity in the human small intestine.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
