Modification of polyacrylonitrile fabric for antibacterial application by tetracycline immobilization

Abstract

In recent years, usage of textile materials that made from synthetic polymers increased rapidly due to these products show good durability, resistant to chemicals, abrasion, tension, shrinkage corrugation. Properties of textile products that made from synthetic polymer could be improved and new features could be added via enzymatic modification. In addition, functional medical textile materials could be improved from modified products using the different bioactive compounds. In this study, enzymatic modification of the polyacrylonitrile (PAN) fabric that use in the textile industry were performed and a new product that has antibacterial properties via tetracycline immobilization was developed. For this purpose, first, enzymatic modification of PAN fabric was performed. Nitrilase was used for modification of PAN fabrics. After drying of PAN fabrics that incubated with nitrilase was taken contact angle measurements, SEM images and ATR-FTIR spectra and examined the modification. Carboxylic acid groups consisted in PAN fabric structure as a result of enzymatic modification and tetracycline was immobilized to carboxylic acid groups using 1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) at optimum reaction conditions. After immobilization, contact angle measurements, SEM images and ATR-FTIR spectra of PAN fabrics were performed. In addition, antibacterial properties of the obtained product were examined.