Modification of Commercial Radiotherapy System for Ultra-High Dose Rate Electron Beam Irradiation

Abstract

<h3>Purpose/Objective(s)</h3> Because electron generation in X-ray mode needs to be about 1000 times more than electron beam mode, modifying commercial radiotherapy system make it possible to irradiate with ultra-high dose rate. This study aimed to show the feasibility of ultra-high dose rate irradiation using a commercial linear accelerator. <h3>Materials/Methods</h3> Removing targets and flattening filters, adjusting source-surface-distance (SSD), and controlling RF driver and electron gun were performed in Simens Oncor® and Varian Clinac iX® radiotherapy system. The irradiation time was adjusted in microseconds through the Arduino-based gating system, and dose rate was confirmed with EBT3 and EBT-XD films. <h3>Results</h3> In 6 MV X-ray mode of Siemens® system, 100.9±3.78 Gy/s electron beam was irradiated at SSD of 60cm. After modifying 10MV X-ray mode in Varian® radiotherapy system, dose rate was 43.1Gy/s at SSD of 100cm. By manually controlling the parameters of the RF driver and electron gun, 318 Gy/s rate of electron beam was irradiated within 15 × 15 cm² of irradiation field at SSD of 100cm. Acquired ultra-high dose rate electron beam exhibits the following characteristics at SSD of 100cm with full opened jaw irradiation: R₅₀ 4.1cm, W₈₀ 9.8cm (vertical) and 9.3cm (horizontal). <h3>Conclusion</h3> We confirmed that FLASH irradiation was feasible by modifying a commercial radiotherapy system, which made further research possible.