Abstract

Today, chitosan (CS) is probably considered as a biofunctional polysaccharide with the most notable growth and potential for applications in various fields. The progress in chitin chemistry and the need to replace additives and non-natural polymers with functional natural-based polymers have opened many new opportunities for CS and its derivatives. Thanks to the specific reactive groups of CS and easy chemical modifications, a wide range of physico-chemical and biological properties can be obtained from this ubiquitous polysaccharide that is composed of β-(1,4)-2-acetamido-2-deoxy-d-glucose repeating units. This review is presented to share insights into multiple native/modified CSs and chitooligosaccharides (COS) associated with their functional properties. An overview will be given on bioadhesive applications, antimicrobial activities, adsorption, and chelation in the wine industry, as well as developments in medical fields or biodegradability.

Highlights

  • Chitosan (CS) is a copolymer of glucosamine and N-acetyl glucosamine branched by β-(1-4)linkages

  • CS, and glucan-CS can be hydrolyzed by enzymes to prepare specific medium and low molecular weight

  • Many scientific publications have explored the production of water-soluble chitouronic acid sodium Oxy-Chitosan with the use of TEMPO, which is an organic catalyst used for the oxidation of hydroxyl functions into aldehyde in NaOCl and NaBr conditions

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Summary

Introduction

Chitosan (CS) is a copolymer of glucosamine and N-acetyl glucosamine branched by β-(1-4). The demineralized and deproteinized chitin is submitted to a second alkaline treatment at high temperature before an optional decolorization step using hydrogen peroxide, sodium hypochlorite, or acetone [5]. All these acidic and alkali treatments are extremely hazardous for the environment and not sustainable. Macromolecules of CS can produce self-assembled structures based on hydrogen-bond networks formation in aqueous solutions, leading to fibers Conformational variations of these CS assemblies have been reported to depend on local environmental changes around CS (e.g., pH, temperature, types of salt, and types of acids). Bioadhesive applications, antimicrobial activities, adsorption, and chelation in the wine industry, as well as developments in medical fields or biodegradability, have been detailed for highlighting the potential of chitosan and derivatives

Extraction and Structure of Chitosan from Natural Sources
Global Market
Chitosan Modification and Functionalization
Chitosan Chemistry
Quaternized Chitosan Derivatives
N-acyl Chitosan Derivatives
Oxy-Chitosan Derivatives
Cross-Linked Chitosan Derivatives
Sedimentation and Flocculation in the Wine Industry
Antimicrobial Functions
Elicitation and Stimulation of Plants
Biomedical
Adhesive Properties
Other Potential Applications
Findings
Conclusions

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