Abstract
BackgroundType 2 diabetes mellitus (T2DM) remains a public health problem in low-income countries, including African countries. Risk factors of this disease in Africa are still unclear. This study will examine the modifiable and emerging risk factors associated with T2DM in Africa.MethodologyThe study will include a systematic review and meta-analysis of published and unpublished empirical studies, reporting quantitative data only. We will conduct a search on scientific databases (e.g. Global Health), general online search engines (e.g. Google Scholar) and key websites for grey literature using a combination of key countries/geographic terms, risk factors (e.g. overweight/obesity) and T2DM (including a manual search of the included reference lists). We will use the Comprehensive Meta-Analysis Software (CMA) version 2.0 for data management and analysis. This protocol follows the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P).DiscussionThe systematic review and meta-analysis will provide a robust and reliable evidence base for policy makers and future research. This may help with identifying and implementing more cost-effective diabetes prevention strategies and improved resource allocation.Systematic review registrationThis protocol has been registered with the PROSPERO international prospective register of systematic reviews. The reference number is CRD42016043027.
Highlights
Type 2 diabetes mellitus (T2DM) remains a public health problem in low-income countries, including African countries
Systematic review registration: This protocol has been registered with the PROSPERO international prospective register of systematic reviews
This is exemplified in a meta-analysis that suggests that two servings of whole grain per day is associated with a 21% lower risk of diabetes [25]
Summary
Type 2 diabetes mellitus (T2DM) remains a public health problem in low-income countries, including African countries. Risk factors of this disease in Africa are still unclear. Once described as a disease of the affluent, type 2 diabetes mellitus (T2DM) has emerged as a significant non-communicable disease (NCD) that is threatening the economic, social and cultural fabric of African populations [1]. Communicable diseases attract the most political attention and resource allocation [13,14,15].
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