Abstract
Modern Trends in Early Diagnosis of Acute Respiratory Distress Syndrome
Highlights
Acute respiratory distress syndrome (ARDS) is a noncardiogenic pulmonary edema, in the basis of which lies an alteration (dystrophy, necrosis, apoptosis) of alveolar epithelium, pulmonary microcirculation endothelium, and their basal membranes (including structures of aerohematic barrier) by endogenous and exogenous aggressive factors, leading to vascular permeability growth and development of acute respiratory failure [1,2]
Acute respiratory distress syndrome (ARDS) is a noncardiogenic pulmonary edema, in the basis of which lies an alteration of alveolar epithelium, pulmonary microcirculation endothelium, and their basal membranes by endogenous and exogenous aggressive factors, leading to vascular permeability growth and development of acute respiratory failure [1,2]
[3] ARDS has remained a critical condition with a high morbidity and mortality [4], which is in great deal due to an inability of the currently used clinical ARDS criteria to detect the early stage of the syndrome
Summary
Acute respiratory distress syndrome (ARDS) is a noncardiogenic pulmonary edema, in the basis of which lies an alteration (dystrophy, necrosis, apoptosis) of alveolar epithelium, pulmonary microcirculation endothelium, and their basal membranes (including structures of aerohematic barrier) by endogenous and exogenous aggressive factors, leading to vascular permeability growth and development of acute respiratory failure [1,2]. [3] ARDS has remained a critical condition with a high morbidity and mortality [4], which is in great deal due to an inability of the currently used clinical ARDS criteria to detect the early stage of the syndrome. The problem of prompt diagnosis is of great significance for critical care medicine: the earlier we diagnose the critical condition, the broader spectrum of treatment approaches we have and the better are the outcomes.
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