Abstract

Abstract. Colorectal cancer (CRC) is one of the most common malignant tumours of the human gastrointestinal tract. The development of colorectal cancer consists of several stages, starting with benign adenomatous polyps in the inner wall of the large intestine and rectum, and then gradually developing into advanced adenoma, carcinoma in situ and invasive carcinoma. The aim of this review of current literature is to consider new routine screening and diagnostic methods (e.g. endoscopy and CT colonoscopy, SEPT9 methylation analysis, faecal test) and to search for reliable molecular markers for early diagnosis of CRC.

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