Abstract
The paper considers modern approaches to the zoning of territories and the selection of people for life in extreme environmental conditions, taking into account modern geopolitical challenges. It is shown that it is possible, based on the allostasis concept, to conduct not only the selection of persons with a high level of nonspecific resistance, but also to quantify the degree of extremity of environmental factors using the standard represpiration test.
 Key words: adaptation, extreme conditions, selection, hypoxia, cold, rerespiration, allostatic load.
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