Abstract
The article presents the results of our studies and literature data in order to evaluate the efficacy and safety of antitussive drug of a new class (Rengalin®) containing release active antibodies to mediators of inflammation to morphine, bradykinin and histamine. Clinical studies in this promising area are not numerous but confirm the results of experimental studies and testify to the efficacy and safety of Rengalin in the cough treatment. The first in Russia clinical study (2012) of the drug Rengalin for the treatment of dry cough in children aged 3 - 10 y.o. (n = 61) with acute respiratory infections (acute rinopharingitis, laryngotracheitis, tracheitis) in a conditions of a clinic showed its clinical efficacy and safety similar to the effect of butamirate citrate (Sinecod®). Data few works of other researchers confirm the data obtained by the authors.
Highlights
В статье представлены собственные результаты исследования авторов, а также данные литературы в отношении оценки эффективности и безопасности противокашлевого препарата нового класса (Ренгалин®), содержащего релиз-активные антитела к медиаторам воспаления морфину, брадикинину и гистамину
The article presents the results of our studies and literature data in order to evaluate the efficacy and safety of antitussive drug of a new class (Rengalin®) containing release active antibodies to mediators of inflammation to morphine, bradykinin and histamine
Data few works of other researchers confirm the data obtained by the authors
Summary
В статье представлены собственные результаты исследования авторов, а также данные литературы в отношении оценки эффективности и безопасности противокашлевого препарата нового класса (Ренгалин®), содержащего релиз-активные антитела к медиаторам воспаления морфину, брадикинину и гистамину. Clinical studies in this promising area are not numerous but confirm the results of experimental studies and testify to the efficacy and safety of Rengalin in the cough treatment. С точки зрения «управления кашлем» большой интерес представляет применение такого нового комбинированного лекарственного препарата, как Ренгалин, созданного на основе антител к медиаторам воспаления, – антитела к морфину (анти-М), брадикинину (анти-В) и гистамину (анти-Н) (ООО «НПФ «МАТЕРИА МЕДИКА ХОЛДИНГ», ЛП-002790; ЛСР006927/10).
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