Abstract
This review highlights the latest developments in current cell culture methods, including three-dimensional culture, organoids, coculture systems, microfluidics, and nanofiber scaffolds to support neuroregeneration in major neuropsychiatric illnesses. Due to the enhanced in vitro modeling of human brain structure and function, these state-of-the-art methods allow for investigations of disease processes and drug screening, and pathophysiological research on neuroregeneration has increased. We examine recent research on the relationship between these technologies and neuropsychiatric conditions such as stroke, Alzheimer’s, traumatic brain injury, and spinal cord injury. The advancements present encouraging prospects for augmenting neuroregeneration and could facilitate stem cell-based therapies for neuropsychiatric ailments that were previously untreatable.
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