MODERN ASPECTS OF THE TREATMENT OF PATIENTS WITH AUTOIMMUNE THYROIDITIS

Abstract

The relevance of the problem is due to the continuous increase in morbidity and the lack of effectiveness of existing treatment methods. The aim of the study is to improve the treatment results of patients with autoimmune thyroiditis by introducing modern laser technology. The study was conducted retrospectively from 2008 to 2021 and is based on data from the examination and treatment of 481 patients with autoimmune thyroiditis. The patients were divided into groups according to the applied treatment methods: the first group - 129 (29,19%) patients, the second group - 106 (23,98%) patients, and the third group - 207 (46,83%) patients. The concentrations of thyroid hormones, pituitary gland and antibodies to thyroid tissues in the blood serum of patients before and after treatment were studied and compared. Long-term treatment results were studied in 340 (70,7%) patients (t=8,8, p≤0,001). Photodynamic therapy, in combination with sessions of intravenous laser blood irradiation with lowintensity laser radiation, contributed to the normalization of thyroid hormone levels (TSH, FT4 and FT3) of the thyroid gland on the 15th day of treatment. Combining conservative treatment of patients with autoimmune thyroiditis with photodynamic therapy allows to obtain good and satisfactory results in 77,5% of cases, which gives reason to recommend photodynamic therapy in combination with sessions of intravenous laser blood irradiation with low-intensity laser radiation as an effective way to complement traditional conservative treatment