Abstract
Introduction:Holistic wound care is one of the ways to prevent gangrene and amputation, modern wound dressing is more effective than convensional with increasing transforming growth factor and cytokine, especially interleukin. This study aims to identify the effectiveness of Modern and Convensional Wound Dressing to Interleukin 1 (IL-1) and Interleukin 6 (IL-6) in Diabetic wound. Method:A Quasi eksperimental pre-post with control group design was used. The intervention given was modern wound dressing and Control group by convensional wound dressing, This study was conducted in Makassar with 32 samples (16 in intervention group and 16 in control group). Result: The result of Pooled T- test showed that p = 0.00 (p < 0.05), it means that there was signifi cant correlation between modern wound dressing to IL-6 and IL-1 than Convensional wound dressing. Discussion: Process of wound healing was produced growth factor and cytokine (IL-1 and IL-6), it will stimulated by wound dressing, modern wound dressing (Calcium alginat) can absorb wound drainage, non oklusive, non adhesif, and autolytic debridement.Keywords: Modern wound dressing, Interleukin 1 (IL-1), Interleukin 6 (IL-6)
Highlights
Holistic wound care is one of the ways to prevent gangrene and amputation, modern wound dressing is more effective than convensional with increasing transforming growth factor and cytokine, especially interleukin
This study aims to identify the effectiveness of Modern and Convensional Wound Dressing to Interleukin 1 (IL-1) and Interleukin 6 (IL-6) in Diabetic wound
International Anesthesia ResearchSociety. (Online). (http:// pt .wk h e a lt h .c o m /pt /r e / lw wg at eway/ landingpage.htm;jsessionid=Vs1J8t2B m3vpTFpQ1ySyTjfGRvlL7Lvjy5yQv7 4JNj1hljG5J2n8!-1552477860!18119562 8!8091!-1?issn=00032999&volume=111 &issue=6&spage=1525. 15 Maret 2012, jam 09.55 WIB)
Summary
Penelitian ini merupakan penelitian kuantitatif dengan menggunakan quasiexperimental design dengan prepost testcontrol group design untuk membandingkan tindakan yang dilakukan sebelum dan sesudah eksperimen. Teknik perawatan luka konvensional adalah teknik perawatan luka yang menggunakan kasa untuk menutup ulkus diabetik. Terdapat perbedaan ekspresi Interleukin 1 antara kelompok perawatan luka konvensional dan perawatan luka modern pada penderita ulkus diabetik di Makasar. Berdasarkan P value tersebut, maka dapat disimpulkan bahwa pada tingkat kepercayaan 95% terdapat perbedaan ekspresi kadar interleukin[1] yang bermakna antara responden yang menggunakan perawatan luka modern dan Teknik Perawatan Luka Modern dan Konvensional (Werna Nontji, dkk.). Terd apat perbed a a n ek spresi interleukin 6 antara kelompok perawatan luka konvensional dan perawatan luka modern pada penderita ulkus diabetik di Makasar. Berdasarkan P value tersebut, maka dapat disimpulkan bahwa pada tingkat kepercayaan 95% terdapat perbedaan ekspresi kadar interleukin 6 yang bermakna antara responden yang menggunakan perawatan luka modern dan responden yang menggunakan perawatan luka konvensional. Distribusi Rata-Rata Interleukin 1 dan Interleukin 6 pada Penderita Luka Diabetik
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