Moderated Poster Session 5.

Abstract

), and its variation gradients (D=D3-D1) as an estimation of the intensity of the cell inflammatory response. For each laboratorial parameter the increasing D values were graded in 50%. MCE study was performed at D3 post ACS with a C256 and 512 Sequoia (Acuson Siemens, Germany) ultrasound machines after intravenous SonoVue® (Bracco, Rovi)continuous infusion during 3´, intermitent digital MCE imag- ing acquisition, Dt=175 ms, Tec imaging condition, and PCI software, with the acquisition of destruction/perfusion sequential images. The MCE pat- tern was classsified in 16 LV wall segments as normal (P0), late filling (P1), heterogeneous (P2) and absence of perfusion (P3), the mean value/pt, per- cent distrubution (%) and the correspondent segmental perfusion index (SPI) were calculated. Results: We observed a direct relationship between SPI and hs-CRP (r=0.44; p=0.01) and DCD40 (r=0.51; p=0.01). Linear regression and multiple corre- lation analysis were applied between hs-CRP and the different MCE pat- terns, with P1/pt (r=0.37; p=0.01), P2/pt (r=0.53; p<0.01) and between CD40 and P1/pt (r=0.42; p=0.01) and P2/pt (r=0.56; p<0.01). Conclusions: In this study we obtained a direct relationship between the intensity of the cell inflammatory response post ACS evaluated by serum markers and the extension of the LV myocardial ischemic area by MCE. This relationship was more significant for the late filling and patchy MCE pat- terns, revealing the presence of a greater myocardial area at risk post ACS by this new non invasive technique.