Abstract

In the current research, spinal cord injury was repaired through a moderate treadmill exercise and carica papaya leaf extract-loaded nanocomposite hydrogel. In vitro studies showed that the carica papaya extract-loaded nanocomposite hydrogel augmented the metabolic function of the cells and showed a gradual degradation. In vivo study showed that the developed treatment strategy promoted spinal cord injury repair as shown in histopathological studies and BBB assay.

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