Moderate Intensity Interval Training (MIIT) and High Intensity Interval Training (HIIT) exercise therapy against irisin levels in obesity

Abstract

Obesity can cause physiological disorders. These physiological disturbances cannot be separated from the roles of irisin. Exercising with the right measure, measurable, and regularly is a strategy for dealing with obesity. The aims of this study were (1) to determine the effect of irisin levels on exercise with the Moderate Intensity Interval Training (MIIT) and High Intensity Interval Training (HIIT) levels models in obese rats. This research is a true experimental laboratory study with a pretest-posttest control group design. This research was conducted at the Bioscience Laboratory of Brawijaya University, Malang. The research sample used 27 obese male Wistar rats divided into 9 MIIT group rats, 9 HIIT rats, and 9 control rats. Exercise intervention is given for 6 weeks at a frequency of 4 times per week. The intensity of MIIT (60–80% of base line ability), HIIT (90–100% of base line ability), irisin levels are obtained from blood tests using enzyme-linked immunosorbent assay (ELISA). Data analysis used the Anova test and post hoc Tukey analysis with a significance level of 0.01. The results showed that there was no significant difference in irisin levels (p = 0.507). The HIIT irisin difference was lower than MIIT (p = 0.932) and Control (p = 0.491), and there was no difference in irisin value between the MIIT and Control groups (p = 0.708).