Abstract
AbstractModels of Alzheimer s disease currently focus on symptomatology, as understanding of the etiology of the disorder is not yet sufficiently advanced to model the disease process in animals. Moreover, currently available treatments are purely palliative in nature. Given that cognitive dysfunction is a central feature of the disease, animal models of cognitive dysfunction are frequently used to evaluate the therapeutic potential of test compounds. This unit presents a rat model in which a brain lesion is produced which disrupts septohippocampal function, thus impairing performance on a spatial learning task (the Morris water maze).
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
