Abstract
A method of permanently implanting colloidal P32 by infusional brachytherapy has been reproduced in the clinic as previously reported ( 1 Order S.E. Siegel J.A. Principato R. et al. Selective tumor irradiation by infusional brachytherapy in nonresectable pancreatic cancer A Phase I study. Int. J. Radiat. Oncol. Biol. Phys. 1996; 36: 1117-1125 Abstract Full Text PDF PubMed Scopus (37) Google Scholar ). Recently the use of macroaggregated albumin before infusing colloidal P32 has been challenged in animal experiments ( 2 Lee I. Wallner P.E. Evaluation of cellular uptake tumor retention, radiation response in tumor pathophysiology and the experimental solid tumors after an intratumoral infusion of colloidal 32P-CP. Cancer. 1997; 80: 2611-2617 Crossref PubMed Google Scholar , 3 Lee I. Lee Y.H. The effect of various therapeutic solutions including Colloidal Chromic 32P via intratumoral injection on the tumor physiologic parameters of AsPC-1 human pancreatic tumors xenographs in nude mice. Clinical Cancer Research. 1999; 5: 3139-3140 Google Scholar ).
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