Abstract
Models of the active transport of neurotransmitters in synaptic vesicles were constructed. The models were used to determine the resting potential at membranes of synaptic vesicles: 40 mV (monoamines and acetylcholine) and −40 mV (glutamate). The potential at the membrane of a synaptic vesicle was almost absent for the transport of GABA and glycine. The neurotransmitter concentration of a cell was 0.1–18 mM at the concentration of neurotransmitters in a vesicle equal to 0.5 M. This result is in qualitative agreement with the relevant experimental data.
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