Abstract

BackgroundPerson-centred care has been shown to be cost-effective compared to usual care for several diseases, including acute coronary syndrome, in a short-term time perspective (< 2 years). The cost-effectiveness of person-centred care in a longer time perspective is largely unknown.ObjectivesTo estimate the mid-term cost-effectiveness of person-centred care compared to usual care for patients (< 65) with acute coronary syndrome, using a 2-year and a 5-year time perspective.MethodsThe mid-term cost-effectiveness of person-centred care compared to usual care was estimated by projecting the outcomes observed in a randomized-controlled trial together with data from health registers and data from the scientific literature, 3 years beyond the 2-year follow-up, using the developed simulation model. Probabilistic sensitivity analyses were performed using Monte Carlo simulation.ResultsPerson-centred care entails lower costs and improved effectiveness as compared to usual care, for a 2-year time and a 5-year perspective. Monte Carlo simulations suggest that the likelihoods of the person-centred care being cost-effective compared to usual care were between 80 and 99% and between 75 and 90% for a 2-year and a 5-year time perspective (using a 500,000 SEK/QALY willingness-to-pay threshold).ConclusionsPerson-centred care was less costly and more effective compared to usual care in a 2-year and a 5-year time perspective for patients with acute coronary syndrome under the age of 65.

Highlights

  • Acute coronary syndrome (ACS) is a diagnosis which comprises ST-segment elevation myocardial infarction (MI), non-segment elevation MI, and unstable angina [1]

  • The Markov-type model developed in this study projects available 2-year clinical data to a 5-year time perspective and computes cost-effectiveness measures of Person-centred care (PCC) provided to patients with ACS under the age of 65

  • The resulting incremental cost-effectiveness ratio for the 5-year time perspective was estimated at SEK-82,292 per qualityadjusted life years (QALYs)

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Summary

Introduction

Acute coronary syndrome (ACS) is a diagnosis which comprises ST-segment elevation myocardial infarction (MI), non-segment elevation MI, and unstable angina [1]. Mortality is elevated among patients with ACS both during the initial hospitalization and (at least) up to 12 years after discharge. Person-centred care has been shown to be cost-effective compared to usual care for several diseases, including acute coronary syndrome, in a short-term time perspective (< 2 years). Objectives To estimate the mid-term cost-effectiveness of person-centred care compared to usual care for patients (< 65) with acute coronary syndrome, using a 2-year and a 5-year time perspective. Monte Carlo simulations suggest that the likelihoods of the person-centred care being cost-effective compared to usual care were between 80 and 99% and between 75 and 90% for a 2-year and a 5-year time perspective (using a 500,000 SEK/QALY willingness-to-pay threshold). Conclusions Person-centred care was less costly and more effective compared to usual care in a 2-year and a 5-year time perspective for patients with acute coronary syndrome under the age of 65

Methods
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Conclusion

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