Abstract
A microwave microstrip sensor incorporating a split ring resonator is presented in this paper for microsphere detection and dielectric characterization within a microfluidic channel. Split ring resonator (SRR) sensor of three different radii, but with approximately equal gap dimensions to change their sensitivity, were designed and fabricated, of resonance frequencies 2.5, 5.0 and 7.5 GHz. To validate the SRR sensors, two sizes of polystyrene microspheres were tested, of diameters 15 and 25 $\mu{\rm m}$ . Measurements of changes in resonance frequency and insertion loss of the odd SRR mode were related to the dielectric contrast provided by the microspheres and their host solvent, here water. COMSOL Multiphysics was used to model the sensors, and good agreements were found between the simulated and measured results.
Highlights
M UCH research has been undertaken in the use of microwave methods for the realization of rapid, reliable, accurate and non-invasive bio-sensors
The dielectric property of a single cell has been investigated by using a microwave biosensor [2], incorporating a capacitive sensing zone for trapped cells within microfluidic channel
We demonstrate a new application for a microwave split ring resonator (SRR) with a narrow, tapered gap section, as a sensor for the dielectric characterization of microparticles
Summary
M UCH research has been undertaken in the use of microwave methods for the realization of rapid, reliable, accurate and non-invasive bio-sensors. Recent use of microwave methods for detecting the dielectric properties of human cells has yielded compelling results [1]. The dielectric property of a single cell has been investigated by using a microwave biosensor [2], incorporating a capacitive sensing zone for trapped cells within microfluidic channel. An original label free bio-sensing approach for cellular study based on micro-technologies at RF frequencies is proposed [4]. This bio-detection method presents advantages in that it is label free and of sub-millimetric size, allowing operation at the cell scale and with a limited number of cells. A cost-effective, scalable microwave system that can be integrated with microfluidic
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