Abstract

AbstractA mathematical model that can be used to describe cell growth in a tower fermentation system with backflow and cell sedimentation is presented. Two computation procedures to determine steady state performance are described and some results are obtained for two‐, four‐ and eight‐stage tower systems. The effects of feed geometry, backflow rate and cell sedimentation on steady‐state behaviour are investigated. The results show that control of backflow, and cell sedimentation within the tower together with control of feed flow rate and feed geometry will allow a wide range of operating conditions to be realised in a tower system.

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