Abstract
The first electrophysiological evidence of the phenomenon of traveling electrical waves produced by populations of interneurons within the spinal cord was reported by our interdisciplinary research group. Two interesting observations derive from this study: first, the negative spontaneous cord dorsum potentials (CDPs) that are superimposed on the propagating sinusoidal electrical waves are not correlated with any scratching phase; second, these CDPs do not propagate along the lumbosacral spinal segments, but they appear almost simultaneously at different spinal segments. The aim of this study was to provide experimental data and a mathematical model to explain the simultaneous occurrence of traveling waves and the zero-lag synchronization of some CDPs.
Highlights
The lumbar spinal cord exhibits spontaneous electrical activity produced by neuronal ensembles located in the dorsal horn
Our study suggests that the spontaneous nCDPs and the sinusoidal cord dorsum potentials (CDPs) could be generated by two different neuronal groups; we do not exclude other neuronal configurations
The spontaneous activity was produced by dorsal horn neurons that responded monosynaptically to stimulation of lowthreshold cutaneous afferents
Summary
The lumbar spinal cord exhibits spontaneous electrical activity produced by neuronal ensembles located in the dorsal horn. Such spontaneous activity was defined with the term “spontaneous cord dorsum potentials (CDPs).”. In subsequent studies by Manjarrez et al (2000, 2003), a detailed analysis on the origin and physiological role of these electrical potentials was performed These authors reported that a 2013 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society
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