Abstract
Aim: To report a correlative model to calculate the solubility of ketoprofen in mono-solvents at various temperatures. Methodology: Previously reported solubility data of ketoprofen in a number of mono-solvents at various temperatures are re-analyzed using a recently developed model employing Abraham, Hansen and Catalan parameters as input values. The accuracy of the model is evaluated by computing the standard deviation of residuals (SDRs) and compared with those of previous models. Results: The new model provided very accurate correlation for the solubility of ketoprofen in the investigated mono-solvents at various temperatures. The obtained SDR is 2.20 where the SDRs of previously reported models are 1.54 to 2.56. The new model correlates whole solubility data using a single model, whereas other models correlate the solubility data in each mono-solvent using a separate set of model constants. Conclusion: The trained model provided reasonably accurate results for ketoprofen by using Abraham, Hansen and Catalan parameters of the mono-solvents as input values.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Revista Colombiana de Ciencias Químico-Farmacéuticas
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
