Abstract

BackgroundInnovations that improve the affordability, accessibility, or effectiveness of health care played a major role in the Millennium Development Goal achievements and will be critical for reaching the ambitious new Sustainable Development Goal (SDG) health targets. Mechanisms to identify and prioritize innovations are essential to inform future investment decisions.MethodsInnovation Countdown 2030 crowdsourced health innovations from around the world and engaged recognized experts to systematically assess their lifesaving potential by 2030. A health impact modeling approach was developed and used to quantify the costs and lives saved for select innovations identified as having great promise for improving maternal, newborn, and child health.ResultsPreventive innovations targeting health conditions with a high mortality burden had the greatest impact in regard to the absolute number of estimated lives saved. The largest projected health impact was for a new tool for small-scale water treatment that automatically chlorinates water to a safe concentration without using electricity or moving parts. An estimated 1.5 million deaths from diarrheal disease among children under five could be prevented by 2030 by scaling up use of this technology. Use of chlorhexidine for umbilical cord care was associated with the second highest number of lives saved.ConclusionsThe results show why a systematic modeling approach that can compare and contrast investment opportunities is important for prioritizing global health innovations. Rigorous impact estimates are needed to allocate limited resources toward the innovations with great potential to advance the SDGs.

Highlights

  • Innovations that improve the affordability, accessibility, or effectiveness of health care played a major role in the Millennium Development Goal achievements and will be critical for reaching the ambitious new Sustain‐ able Development Goal (SDG) health targets

  • The Millennium Development Goals (MDGs) showed the world what we can accomplish by galvanizing attention, resources, and accountability to accelerate progress toward a common set of health targets

  • In 2015, PATH and Applied Strategies collaborated to model eight innovations, addressing five different health conditions, for the potential to contribute to reaching SDG health targets (Table 1)

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Summary

Introduction

Innovations that improve the affordability, accessibility, or effectiveness of health care played a major role in the Millennium Development Goal achievements and will be critical for reaching the ambitious new Sustain‐ able Development Goal (SDG) health targets. Goal 3 for health and well-being has targets ranging from reducing maternal mortality to ensuring “access to quality essential healthcare services and access to safe, effective, quality, and Herrick et al Cost Eff Resour Alloc (2017) 15:12 affordable essential medicines and vaccines for all.”. Fulfilling these goals will require investing in promising new vaccines, drugs, diagnostics, devices, and other innovations, as well as expanding access to existing interventions that have already proven themselves to be safe and effective Goal 3 for health and well-being has targets ranging from reducing maternal mortality to ensuring “access to quality essential healthcare services and access to safe, effective, quality, and Herrick et al Cost Eff Resour Alloc (2017) 15:12 affordable essential medicines and vaccines for all.” Fulfilling these goals will require investing in promising new vaccines, drugs, diagnostics, devices, and other innovations, as well as expanding access to existing interventions that have already proven themselves to be safe and effective

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