Modeling of the fluid structure interaction of a human trachea under different ventilation conditions

Abstract

This work is focused on the analysis of the response of the tracheal wall to different ventilation conditions. Thus, a finite element model of a human trachea is developed and used to analyze its deformability under normal breathing and mechanical ventilation. The geometry of the trachea is obtained from computed tomography (CT) images of a healthy man. A fluid structure interaction approach is used to analyze the deformation of the wall when the fluid (in this case, air) moves inside the trachea. A structured hexahedral-based grid for the tracheal walls and an unstructured tetrahedral-based mesh with coincident nodes for the fluid are used to perform the simulations with the finite element-based commercial software code (ADINA R & D Inc.). The tracheal wall is modeled as a fiber reinforced hyperelastic solid material in which the anisotropy due to the orientation of the fibers is introduced. Deformation of the tracheal walls is analyzed under different conditions. Normal breathing is performed assuming a sinus shape of the pressure at the inlet and air speed at the outlet based on real data which represent the inspiration and the expiration processes respectively. Mechanical ventilation is simulated as smooth square shape velocity airflow considering positive values of pressure using data from a mechanical ventilation machine. Deformations of the tracheal cartilage rings and of the muscle membrane, as well as the maximum principal stresses in the wall, are analyzed. The results show that, although the deformation and stresses are quite small for both conditions, forced ventilation does not exactly imitate the physiological response of the trachea, since with always positive pressure values the trachea does not collapse during mechanical breathing.