Abstract
The diffusion and adsorption of a virus to a cell is not well represented by the existing models. A complete model, which takes into account the finite thickness of the stagnant boundary layer, the virus concentration profile in that layer, the depletion of the virus concentration at the liquid-cell interface, the initial virus concentration in the film, and the receptor-viral ligand interaction was therefore developed and validated. This model could be fitted to experimental results. It permitted for the first time to determine the viral adsorption kinetics coefficient, and showed that adsorption plays an important role in viral infection process. It also revealed an acceleration phenomenon that takes place during the diffusion/adsorption process under specific conditions.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
