Abstract

High Blood Pressure (HBP) over a long period of time leads to a medical condition known as Hypertension (HTN or HT), in which the arterial blood pressure is persistently inflated. In this research, a blood pressure biosensor has been implemented that monitors the different stages of hypertension by measuring the varying blood pressure values. Further, a system design has been proposed for the theranostics (combination of diagnosis and therapy) of hypertension. The proposed sensor takes blood pressure as the input, and gives the corresponding electrical signal variations at the output, so as to detect the exact stage of hypertension. The working principle of this BP sensor is based on the electrostatic transduction mechanism. The proposed system aims to design a low-cost, easily available, implantable lab-on-chip (LoC) platform for the continuous measurement of blood pressure by keeping track of the patient history, so as to prevent chronic hypertensive disorders. Further, such an implantable LoC theranostic platform is among the best possible solutions for the e-healthcare systems, owing to its potential in a wireless body area network (WBAN) using Internet of Things (IoT) and other similar technologies.

Highlights

  • Blood pressure (BP) is defined as the pressure exerted upon the blood vessels walls due to the circulation of blood

  • Hypertension (HTN or HT), known as high blood pressure (HBP), is basically defined as an abiding medical condition that can cause the insistent increase of BP in the arteries [6]

  • These bands are the indications of particular stages of hypertension, and can be applied further as input to an implantable drug delivery system that will give the medicine to the patient according to the particular type of band

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Summary

Introduction

Blood pressure (BP) is defined as the pressure exerted upon the blood vessels walls due to the circulation of blood. BP is generally measured in mmHg (millimetres of mercury) It is expressed in terms of the systolic (maximum) pressure over diastolic (minimum) pressure. Due to a disease state, a low BP condition is known as hypotension, while persistent high BP condition is referred to as hypertension [5]. Both of these conditions arise because of several mild or severe causes, and can persist in a person over a long duration, or may be of abrupt onset. Hypertension (HTN or HT), known as high blood pressure (HBP), is basically defined as an abiding medical condition that can cause the insistent increase of BP in the arteries [6]. Hypotension over a long term is less prevalent than longterm HTN

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