Modeling of light propagation in turbid medium using Monte Carlo simulation technique

Abstract

The aim of the current study is to simulate the laser photon through biological tissue during PDT therapy using Monte Carlo simulation technique. The model is coded using MATLAB. Interaction of laser light with turbid medium e.g. human tissue depends on the optical properties of the medium i.e. refractive index n, absorption coefficient μa, scattering coefficient μs and anisotropy factor g. Laser light transport through tissue is governed by the radiative transport equations based on absorption and scattering. Direct sampling is used for step-size generation before interaction via absorption or scattering with the transmitting medium, for deflection and azimuthal angle (θ and ϕ) when the scattering even occurs. The tissue medium considered is divided into radial, axial and angular grid elements and an infinite narrow beam with normal incidence on the tissue is considered. The laser light absorbance inside the tissue, reflectance at the top boundary of the tissue and transmittance at the bottom are estimated and these quantities are shown varying radially and angularly. Results of reflectance, transmittance and fluence are compared with the already published results to confirm the authenticity of our coding and these results are found to lie at only 3–4% error.