Modeling of highly sensitive surface plasmon resonance (SPR) sensor for urine glucose detection

Abstract

This work presents a novel structure of surface plasmon resonance (SPR) sensor for urine glucose detection. The structure consists of four layers namely gold, molybdenum disulfide (MoS2), h-BN (hexagonal boron nitride), and graphene. Here, the few-layer h-BN is used as a capping layer over the MoS2 layer. The present sensor performance has been evaluated for sensitivity, quality parameter, resonance angle shift, and accuracy of detection. Sensitivity for urine glucose concentration of 0–15 mg/dl (normal range), 0.625 g/dl, 1.25 g/dl, 2.5 g/dl, 5 g/dl and 10 g/dl are found to be 180 degree/RIU, 183.34 degree/RIU, 185.71 degree/RIU, 187.5 degree/RIU, 190.9 degree/RIU and 194.12 degree/RIU respectively. The corresponding values of quality parameters and detection accuracy are observed 14.88 /RIU, 15.15 /RIU, 15.35 /RIU, 15.5 /RIU, 15.78 /RIU, 16.04 /RIU and 0.07448, 0.09091, 0.10744, 0.12397, 0.17355, 0.27273 respectively. Hence, these enhanced performances of the present SPR biosensor makes this structure suitable for urine glucose detection as well as open a new platform in the field of medical science.